A single type of chemical structure that shows up again and again in modern medicine is the amide bond that links a carbonyl ...
编辑丨王多鱼排版丨水成文酰胺键(amide bond)是有机化学与生物化学中至关重要的化学键,广泛存在于蛋白质、多肽及大多数药物分子中。2026 年 1 月 29 ...
The synthesis and subsequent functionalisation of amides have emerged as pivotal areas in modern synthetic chemistry, enabling the direct conversion of these otherwise inert functional groups into ...
A pair of copper catalysts can create chiral amides in a new, light-driven process, offering a useful alternative to the standard method for making these staples of medicinal chemistry (Nature 2021, ...
The authors’ approach is deceptively simple: take an aldehyde dehydrogenase enzyme, which naturally converts aldehydes to acids, and get it to react with an amine instead of water. But actually making ...
Amides are among the most ubiquitous functional groups in organic chemistry, forming the backbone of peptides and playing a vital role in pharmaceutical, synthetic and materials chemistry. Their ...
Linking molecular components through amide bonds is one of the most important reactions in research and the chemical industry. Scientists have now introduced a new type of reaction for making amide ...
Researchers at the Biocatalysis group led by Dr Francesco Mutti at the Van ‘t Hoff Institute for Molecular Sciences (University of Amsterdam) have developed a novel use of alcohol dehydrogenase (ADH) ...
CAMBRIDGE, Mass.--(BUSINESS WIRE)--Amide Technologies, a leading biotech company specializing in the synthesis of complex peptides, announced today the appointment of Dr. Brad Pentelute as its new CEO ...
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