Cancer cells survive therapy by dynamically rewiring their metabolism in response to nutrient availability, ...

When a neuron ages, it loses synaptic connections with other neurons, it is less able to transmit nerve impulses, and its metabolism is also altered. This process of neuronal ageing — inevitable with ...

Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of ...

Novel protein biomarkers for early detection of pancreatic ductal adenocarcinoma using longitudinal serum protein measurements and machine learning. This is an ASCO Meeting Abstract from the 2025 ASCO ...

Tumor growth unfolds within a tumor microenvironment (TME) defined by metabolic–immune crosstalk. Emerging evidence indicates that cancer cells not only reprogram glycolysis but also alter amino acid, ...

Researchers developed a way to directly reprogram human glial cells into PV interneurons without passing through a stem‑cell stage.

One reason that chronic pain, mental or physical is consistently solvable is the brain’s property of neuroplasticity. Your brain physically constantly changes based on the nature of the sensory input.

Taking care of oneself requires a multi-faceted approach: brain, heart, and metabolic health. What research in 2024 has shown us is that improving our health in these areas comes down to three main ...

A mechanism underlying neutrophil reprogramming in brain cancers has been uncovered, illuminating potential therapeutic targets to stop their pro-cancer effect. Tumor-infiltrating neutrophils are ...

Metabolic reprogramming in fibrotic lung diseases involves key metabolites like lactate, succinate, and 2-hydroxyglutarate, driving inflammation and fibroblast activation. Lactate accumulation ...