Plerixafor (Mozobil, Sanofi, Cambridge, MA, USA) is a small molecule that reversibly disrupts the interaction of CXCR4 with its ligand SDF-1, allowing the release of SCs from the marrow. 12 It is ...

A test measuring proteins in spinal fluid may help support the diagnosis of MS, especially in patients whose disease is harder to diagnose.

CRISPR/Cas9-Mediated GM-CSF knock-out (GM-CSF ko) CAR-T cells demonstrate reduced apoptosis and enhanced in vivo anti-tumor activity in preclinical models Phase 3 SHIELD study utilizing lenzilumab to ...

Researchers identify tanycytes as a critical mechanism for clearing toxic tau protein from the brain, offering a new target ...

Researchers from the MPI of Biochemistry and the Technical University of Munich have discovered new diagnostic markers for multiple sclerosis (MS), a disease that affects 3 million people worldwide.

The data for this retrospective observational study were obtained from the electronic health records (EHRs) of patients with colorectal cancer who received chemotherapy at Texas Oncology. The EHR ...

In a recent study published in Jama Network, researchers investigated the impact of coronavirus disease 2019 (COVID-19) on biomarkers in the cerebrospinal fluid (CSF). Study: Viral Antigen and ...

Impact of Broadening Trial Eligibility Criteria on the Inclusion of Patients With Brain Metastases in Cancer Clinical Trials: Time Series Analyses for 2012-2022 Effective diagnosis, prognostication, ...

Cerebrospinal fluid (CSF) analysis has perhaps the strongest diagnostic and prognostic potential for Alzheimer disease to date, yet some think the field is not harnessing its full power because ...