Cancer is often thought of as a single disease. Yet even tumors that arise in the same organ can follow very different ...

An extensive tumor genomic analysis of individuals with ovarian cancer, led by researchers from Huntsman Cancer Institute at the University of Utah (the U) and Emory University, revealed that Black ...

What happens to the thousands of intestinal cells that have tumour-initiating DNA mutations? A study in mouse models shows that most are eliminated by strong negative selection, but those that survive ...

Some 17 million Americans are living with genetic mutations tied to an increased risk of getting cancer, Cleveland Clinic researchers warned Monday. And the more than 3,400 mutations identified – ...

Despite the significance of immune checkpoint inhibitors (ICIs) in solid tumor treatment, identifying ICI-sensitive populations remains a challenge. Mutations in DNA damage response (DDR) pathway ...

UC San Diego professor Ludmil Alexandrov will lead an international team of scientists awarded $25 million to research cancer mutations. The award comes from Cancer Grand Challenges, a collaboration ...

Chronic inflammation can raise a person's risk of cancer, and a new study reveals key details about how that might happen in ...

A gene known as CTNNB1 encodes for a crucial protein called β-catenin, which has an important role in controlling tissue repair and cell growth. If this gene and its protein are dysfunctional, it can ...

Nearly 1,000 patients seeking care at Penn Medicine have a genetic condition known as Lynch syndrome — a diagnosis linked to higher risks of several cancers. That’s almost triple the number diagnosed ...

Sarah Diepstraten receives funding from the National Health and Medical Research Council, Cure Cancer Australia and My Room Children's Cancer Charity. John (Eddie) La Marca receives funding from ...

This article was published in Scientific American’s former blog network and reflects the views of the author, not necessarily those of Scientific American All cancers share ten underlying principles, ...