eLife

Replication stress-inducing ELF3 upregulation promotes BRCA1-deficient breast tumorigenesis ...

ELF3 axis enables luminal progenitor transformation in BRCA1-deficient breast cancer by reducing genomic instability and promoting progenitor identity.
Technology Networks

Critical Coordinator of DNA Repair During Cell Division Identified

Researchers at The Institute of Cancer Research, London identified the CIP2A–TOPBP1 complex as a master regulator of DNA repair during mitosis, coordinating backup pathways that protect chromosomes ...

Analysis provides new insights into the replication of BK polyomavirus, a major cause of ...

BK polyomavirus, or BKPyV, is a major cause of kidney transplant failure. There are no effective drugs to treat BKPyV.
Nanowerk

Engineered RNA sensor detects and fights coronavirus inside living cells

The technology, called the Viral-Engineered RNA-based Activation System (VERAS), hijacks the virus's own replication ...
AZoLifeSciences on MSN

Synthetic RNA platform converts viral replication into detectable cellular signals

The technology, called the Viral-Engineered RNA-based Activation System (VERAS), hijacks the virus's own replication ...