The capacity of an organism to regenerate depends on cell dedifferentiation followed by proliferation. Mammals, in general, have limited regenerative capacity. Now, a team of researchers at the Salk ...

In a bid to treat blindness, Life Biosciences will try out potent cellular reprogramming technology on volunteers.

A team led by researchers has discovered that a group of cells located in the skin and other areas of the body, called neural crest stem cells, are the source of reprogrammed neurons found by other ...

Scientists reverse eye cell aging with ER-100 gene therapy that reprograms retinal neurons to younger states, offering hope ...

Life Biosciences is pushing cellular rejuvenation into the clinic with ER-100, an experimental gene ...

Both Natural and Experimental Processes Stand to Benefit from Greater Understanding of Nongenetic Factors The mechanisms that ensure that cells from multicellular organisms are genetically homogenous, ...

Studies on diseases that affect the human brain are usually based on animal models which cannot reproduce the complexity of human neuropathies. Therefore, these methodologies often fail when applied ...

An international team led by researchers at Lund University in Sweden has identified the molecular tools needed to reprogram ordinary cells into specialized immune cells. The discovery, published in ...

Scientists have observed signs of rejuvenation in the pancreas, liver, spleen, and blood of mice after applying one cycle of cell reprogramming. To achieve this, the researchers have characterized ...

Modulation of a single amino acid in the reprogramming factor Kruppel-like factor 4 (KLF4) has been demonstrated to markedly improve natural transcription factor function and to result in faster and ...

Researchers from Japan reveal that they may just have found a way to repair cardiac damage in patients suffering from chronic heart attack and heart failure. In a study published in Circulation, ...