本文系统性阐述了实现高产率、高保真度mRNA-DNA杂合折纸纳米结构（mRNA–DNA hybrid origami）的关键设计原则与标准化合成方案。研究通过使用成熟的萤火虫荧光素酶（fLuc）、增强型绿色荧光蛋白（EGFP）和mCherry的mRNA作为支架，设计了五种不同尺寸、形状、交叉 ...

How does the cell convert DNA into working proteins? The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But ...

The two most successful coronavirus vaccines developed in the U.S. – the Pfizer and Moderna vaccines – are both mRNA vaccines. The idea of using genetic material to produce an immune response has ...

Researchers at Arizona State University’s (ASU) School of Molecular Sciences and the Biodesign Institute’s Center for the Mechanism of Evolution have discovered an unprecedented pathway producing ...

DNA and RNA vaccines use genetic material to deliver information to human cells and elicit an immune response. DNA vaccines are safe, easy, affordable to produce, and, unlike RNA vaccines, are stable ...

Biopharma has been quickly ramping up investment in messenger RNA (mRNA), the defining technology behind the Moderna and Pfizer-BioNTech SARS-CoV-2 vaccines. With big plans for mRNA-based therapies, ...

The two most successful coronavirus vaccines developed in the U.S. – the Pfizer and Moderna vaccines – are both mRNA vaccines. The idea of using genetic material to produce an immune response has ...

Holly has a degree in Medical Biochemistry from the University of Leicester. Her scientific interests include genomics, personalized medicine, and bioethics.View full profile Holly has a degree in ...