This is a summary of: Liu. H. et al. Viral RNA blocks circularization to evade host codon usage control. Nature https://doi.org/10.1038/s41586-025-09809-y (2025).

A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...

A research team has developed DeepCodon, a deep learning–based codon optimization tool that significantly improves heterologous protein expression in Escherichia coli while preserving functionally ...

Researchers discover a unique genetic code in Antarctic archaea that encodes a rare amino acid, potentially advancing protein ...

A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...

Alltrna is advancing a new class of genetic medicines based on the power of tRNA biology to universally treat Stop Codon Disease, which encompasses thousands of genetic diseases caused by a premature ...