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AI大模型助力蛋白质设计:ESM-scan工具让氨基酸突变预测更简单高效
近年来,深度学习在蛋白质结构预测和设计领域取得了革命性进展。然而,预测特定位点突变对蛋白质稳定性和功能的影响仍然是一个未解决的挑战。本文介绍了一个新型工具ESM-scan,它利用ESM语言模型来快速高效地预测氨基酸突变的影响。 研究背景与意义 蛋白 ...
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