Formaldehyde's toxicity was presumed to derive from its ability to crosslink DNA, but that happens only at huge doses. Recent discoveries that formaldehyde is found in the body in small amounts led a ...

In the body, the small molecule formaldehyde (upper left in box) inhibits an enzyme (violet) that makes methyl groups (red) that are added to DNA. This interferes with methylation, an important ...

Cell growth requires the synthesis of essential biomolecules, such as nucleotides and amino acids. The 1C unit supplied by the 1C cycle is one of the basic building blocks to make such molecules. This ...