Glycogen, a hyperbranched polymer of glucose, plays a central role as an energy reserve across diverse organisms. In Escherichia coli, its biosynthesis is linked not only to energy storage but also to ...

A new study from scientists at the Buck Institute for Research on Aging has revealed a surprising player in the battle against Alzheimer's disease and other forms of dementia: brain sugar metabolism.

In a scientific first, researchers from Vanderbilt University and the University of California, San Diego, have generated a high-resolution metabolic "map" of how cells orchestrate glucose processing, ...

In a new study published in Nature Metabolism titled “Neuronal Glycogen Breakdown Mitigates Tauopathy via Pentose Phosphate Pathway-Mediated Oxidative Stress Reduction,” researchers from the Buck ...

An international research team has uncovered new insights into healthy brain aging. The researchers found that aging leads to ...

A surprising discovery about how brain cells handle sugar could shift how scientists approach dementia and Alzheimer’s treatments. In a new study published in Nature Metabolism, researchers uncovered ...