The highway handles an enormous volume of freight and passenger traffic. More than 12 million commercial trucks travel the ...

SULLIVAN COUNTY, Tenn. (WJHL) — Seven commercial vehicles were involved in a pileup on Interstate 81 in Sullivan County ...

Traffic is being diverted off of Interstate 81 Northbound at exit 63 due to a jack knifed tractor-trailer, according to ...

Maryland's recently released six-year transportation plan still includes the next phase of widening I-81 in Washington County ...

(WBRE/WYOU) — Three deadly crashes on Interstate 81 near Hazleton in a week; that’s raising concerns and questions as to what, if anything, is happening on that stretch of the interstate, especially ...

A Georgia woman led local law enforcement on a pursuit Friday on Interstate 81 traveling at speeds exceeding 100 miles per ...

Two decades ago, Virginia considered a public-private partnership that would have added two lanes in either direction on Virginia’s 325 miles of Interstate 81. The plan also would have used tolls and ...

KNOXVILLE, Tenn. (WATE) — Two people were injured in a crash that involved an overturned semi-truck and closed Interstate 81 ...

There will be overnight lane restrictions on Interstate 81 northbound and southbound at Exit 170 (Bear Creek/Wilkes-Barre/Route 309) from 8 p.m. to 6 a.m. Monday through Friday for structural work, ...

If you’ll be travelling to or from Maryland via Interstate 81 this Wednesday, you’ll likely encounter a lane closure. PennDOT said the right lane on Interstate 81 at Mason ...