Pancreatic cancer may evade the immune system not by accident but by actively switching off internal danger signals through ...
The cancer gene MYC camouflages tumours by suppressing alarm signals that normally activate the immune system. This finding ...
CARD14 directly binds and regulates MYC, a protein involved in controlling cell growth that can contribute to cancer when it malfunctions. A study published in Cell Reports shows that the proper ...
Beyond direct approaches, the review also emphasizes indirect targeting strategies, including inhibition of MYC transcription or translation, promotion of protein degradation, and synthetic ...
Show More From the Department of Cell & Tissue Biology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA; the Department of Cell & Tissue ...
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MYC gene's dual role in cancer growth and immune suppression
The cancer gene MYC camouflages tumors by suppressing alarm signals that normally activate the immune system.
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