Global and genetic analyses link low physical activity to rising heart disease mortality, while higher activity levels appear ...

Genetic and clinical data suggest dietary factors may influence autism risk via immune pathways, highlighting the need for ...

A new study identifying 56 non-clinical risk factors associated with sudden cardiac arrest (SCA), spanning lifestyle, physical measures, psychosocial factors, socioeconomic status, and the local ...

It has been argued that survival bias may distort results in Mendelian randomization studies in older populations. Through simulations of a simple causal structure we investigate the degree to which ...

Hyperuricemia may causally contribute to PAH, positioning uric acid as a potential therapeutic target for treatment and prevention. Mendelian randomization analysis suggests a genetic-level causal ...

Increased BMI and IBD have causal effects on the risk of hidradenitis suppurativa, as shown by Mendelian randomization analysis. Moderate genetic correlations were found between HS and BMI, smoking, ...