This Collection supports and amplifies research related to SDG 3: Good Health & Wellbeing. The human genome is a vast landscape, with less than 2% of its sequence encoding proteins. For many years, ...

The study shows that a long non-coding RNA called CISTR-ACT acts as a master regulator of cell size, influencing how large or small cells grow across multiple tissues.

These genes are part of the non-coding genome, which makes up about 98% of our DNA and was long dismissed as “junk.” This new ...

What keeps our cells the right size? Scientists have long puzzled over this fundamental question, since cells that are too large or too small are linked to many diseases. Until now, the genetic basis ...

But only a tiny percentage of our DNA – around 2% – contains our 20,000-odd genes. The remaining 98% – long known as the non-coding genome, or so-called ‘junk’ DNA – includes many of the switches that ...

Researchers have identified elusive DNA switches in brain support cells that influence genes tied to Alzheimer’s disease. When people think about DNA, they often picture genes that determine our ...

We’re celebrating 180 years of Scientific American. Explore our legacy of discovery and look ahead to the future. In 1957, just four years after Francis Crick and other scientists solved the riddle of ...