在前人工作的基础上,英茂盛业(inovogen)进一步优化了real-time PCR检测miRNA的方法,成功采用双特异性polyA加尾法检测成熟和前体miRNA。该方法与原有的方法相比,实验成本更低、工作流程简便、特异性更高。 miRNA(microRNA)是一类极小的非编码RNA,具有多种生物 ...
Researchers with an interest in unraveling gene regulation in human health and disease are expanding their horizons by closely looking at alternative polyadenylation (APA), an under-charted mechanism ...
Meet PolyA-miner, a new computational tool that enables scientists to evaluate the contribution of alternative polyadenylation to gene regulation in health and disease. Researchers with an interest in ...
A new proof is given of the existence of Pólya peaks of an (increasing) function $g(t)$. This approach yields several applications, including a characterization of ...
Professor Emmanuel Candès from Stanford University and Professor Terence Tao from University of California, Los Angeles (UCLA) were the 2010 recipients of the George Pólya Prize, which was awarded at ...