Type 2 diabetes (T2D) and obesity are metabolic conditions with many causes, including overlapping and distinct genetic features. A polygenic risk score (PRS) can capture multiple genetic risk factors ...

Prospective Study of Homologous Recombination Repair Gene Mutation Prevalence in Patients With Advanced Prostate Cancer From Latin America: Challenges and Future Approaches A model of absolute risk ...

The new tool could help predict obesity-related health risks earlier and reshape prevention strategies, researchers say. The ...

A new study looked at 926 polygenic risk scores for 310 diseases. It found that, on average, only 11% of individuals who develop disease are identified, while at the same time 5% of people who do not ...

Polygenic risk scores, which estimate a person’s disease risk based on thousands or millions of common genetic variants, perform poorly in screening and prediction of common diseases such as heart ...

Decipher score as a predictor of response to treatment intensification in the NRG Oncology-RTOG 0534 (SPPORT) phase III randomized post-prostatectomy salvage radiotherapy trial. Continuous MMAI scores ...

New polygenic risk scores for obesity, type 2 diabetes, and related complications developed by researchers at Mass General Brigham have effectively identified at-risk individuals. Increasing ...

Depression severity and cardiovascular risk link identified in Type 2 diabetes patients. Learn how mental health may ...