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4月
Systema框架:超越系统性变异评估遗传扰动响应预测的新范式
本研究针对功能基因组学中遗传扰动转录响应预测的挑战,开发了Systema评估框架。研究人员发现现有方法易受系统性变异(systematic variation)干扰,导致预测性能被高估。通过量化10个数据集中的系统性变异,团队揭示了标准评估指标(PearsonΔ、PearsonΔ20)的局限 ...
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