The impact of addiction on the brain is both catastrophic and comprehensive. When the brain is damaged by an addicting chemical, its executive functions—including judgment, decision making, and ...

Cocaine addiction may persist because the drug rewires brain circuits through a protein called DeltaFosB. This buildup ...

Explore the connections between the world of neuroscience and nuances of substance use disorders with our inaugural episode of In Such a Place. We’ll speak with Dr. Anna Radke, a leading expert in the ...

Scientists have developed a new gene therapy that quiets pain at its source in the brain—without the addictive risks of opioids. Using AI to map how pain is processed, they created a targeted “off ...

Addiction decreases the brain’s ability to experience natural, healthy pleasure, driving increased cravings and compulsive substance use. But can this brain deficit be healed? New research from my lab ...

Addiction is often debated as either a disease or a choice, but in reality, it involves elements of both. Many people first ...

Within the brain, chemical neurotransmitters like dopamine and norepinephrine regulate mood, emotions and many physiological and behavioral processes. Their imbalance can contribute to anxiety, ...

In a comprehensive study encompassing over 25 years of research, scientists at Vilnius University's Life Sciences Centre have provided groundbreaking insights into the biological foundations of ...

Researchers have used mouse models to study how cocaine addiction alters the brain, illuminating why relapse is common as well as possible treatment options.

The opioid epidemic is devastating America. Overdoses have passed car crashes and gun violence to become the leading cause of death for Americans under 55. The epidemic has killed more people than HIV ...

An international research team led by the Universitat Jaume I (UJI) has shown that the cerebellum, contrary to what was thought, fulfils functions that go beyond the motor sphere and can be ...