A wave of spatial transcriptomics studies has produced gene-expression atlases that span entire organs and whole organisms, ...

A team of researchers has constructed the most detailed single-cell map of the adult human prostate to date, cataloging more ...

Andreas Pfenning discusses the techniques being developed and used to study neuronal heterogeneity and the therapeutic potential of his work.

Knowing the location of a gene within intact tissue or a single cell allows scientists to unlock unknown cellular functions. This information is often lost in most genetic sequencing techniques, but ...

Transcriptomics is the study of the transcriptome, which is the complete set of RNA transcripts produced by the genome at a specific time or under particular conditions. It involves the analysis of ...

Nova-ST, a new spatial transcriptomics technique, has been introduced by researchers based at Vlaams Instituut voor Biotechnologie (VIB), Katholieke Universiteit (KU) Leuven. According to the ...

Applying single-cell RNA sequencing has led researchers to be able to profile the entire transcriptome of cells. However, these transcriptomes prove difficult to link back to their original location ...

Researchers developed an analytic framework for spatial-omics data that can help to map biological activity within tumors.

This figure shows how the STAIG framework can successfully identify spatial domains by integrating image processing and contrastive learning to analyze spatial transcriptomics data effectively.

Researchers at the Max Delbrück Center have developed an open-source spatial transcriptomics (ST) platform, called Open-ST, that creates 3D molecular maps from patient tissue samples with subcellular ...