mRNA-4157的积极结果，凸显了肿瘤治疗领域的未满足需求，mRNA肿瘤疫苗的市场潜力正被行业广泛看好。麦高证券研报指出，mRNA肿瘤疫苗有潜力成为泛癌种、高可及性、现货化与个性化兼具的新型肿瘤免疫疗法。其可凭借广泛的联用，以辅助疗法切入临床，逐步 ...

Moderna和默沙东（MSD）今日公布了2b期KEYNOTE-942/mRNA-4157-P201研究的中位五年随访数据。该研究评估了在高风险黑色素瘤（III/IV期）患者完成根治性切除后，在研mRNA个体化癌症疫苗intismeran autogene（mRNA-4157或V940）联合PD-1抑制剂Keytruda（pembrolizumab）的疗效与安全性。分析显示，在中位随访5年时，与K ...

When U.S. Health Secretary Robert F. Kennedy Jr. announced on Aug. 5 that nearly $500 million to research mRNA vaccines would be canceled, it was one in a continuing line of moves that have put his ...

Kendra Pierre-Louis: For Scientific American’s Science Quickly, I’m Kendra Pierre-Louis, in for Rachel Feltman. Cancer: it’s a diagnosis that most of us have learned to fear. On the one hand decades ...

The Department of Health and Human Services has defended cuts to vaccine research with statements that mislead on the safety of mRNA technology, despite an extensive history of testing. “After a ...

mRNA vaccine companies are overhyped post-pandemic, facing scientific, operational, and regulatory headwinds that limit long-term investment appeal. Scientific and business risks, including delivery ...

Many public health experts and scientists say they are stunned by Health Secretary Robert F. Kennedy Jr’s decision to cancel nearly half a billion dollars in federal funding for future vaccine ...

Robert F. Kennedy Jr. has halted funding for mRNA shots. We explore why. By Adam B. Kushner I’m the editor of this newsletter. Robert F. Kennedy Jr., the health secretary, isn’t just a vaccine skeptic ...

The U.S. government is divesting from mRNA vaccines, but will other uses of the technology be spared? In a time of uncertainty, scientists worry that revolutionary treatments for cancer, immune ...