本研究针对牙周炎中炎症与细胞功能失调的机制,探讨了METTL3介导的DSC1基因m6A修饰的关键作用。研究人员通过临床样本和细胞模型发现,METTL3通过m6A修饰增强DSC1 mRNA稳定性,从而缓解LPS诱导的细胞损伤、凋亡及炎症因子释放。该研究揭示了表观遗传调控在牙周炎 ...
Our purpose was to investigate if dysregulation of cell adhesion molecules could be linked to prognosis in squamous cell carcinomas (SCCs) of the anal region. To analyse protein expression of DSG1, ...