In an exclusive, wide-ranging interview with Lester Holt, President Joe Biden discusses the growing number of states rolling back mask requirements, the tense standoff with Russia over Ukraine, skyrocketing inflation, where he is in his search for a Supreme Court nominee and more. | NBC Nightly News with Tom Llamas

Lester Holt interviews Dr. Anthony Fauci about the new coronavirus variant which led President Biden to impose travel restrictions for South Africa, and seven other countries. | NBC Nightly News with Tom Llamas

In his first interview since the election, President-elect Joe Biden tells Lester Holt that he felt confident while waiting for the results. Watch more from the exclusive interview: https://nbcnews.to/3l8cUcX | NBC Nightly News with Tom Llamas

Vice President Kamala Harris spoke exclusively with Lester Holt to discuss her first trip overseas, how the administration is addressing the immigration crisis, and if she plans to visit the southern border herself. | Today Show

TONIGHT: Lester Holt sits down with Vice President Harris in an exclusive interview as she leads diplomatic efforts to address the surge of migrants into the U.S. Tune in to NBC Nightly News at 6:30 pm ET / 5:30 pm CT (check your local listings). | NBC Nightly News with Tom Llamas