Research studies are now using polygenic risk scores to determine a person’s inherited risk for certain diseases, but there are inconsistencies in how these scores are calculated. NHGRI has published guidelines in Nature for how these scores should be reported. https://bit.ly/3qyxrtR | National Human Genome Research Institute

A polygenic risk score gives an estimate of a person’s risk for diseases based on their genomic variants, or the tiny differences in our DNA. Many recent studies include polygenic risk scores, and NHGRI is working to make sure this research can benefit clinical care! Learn more about polygenic risk scores in our updated Talking Glossary! https://go.usa.gov/xuyGp | National Human Genome Research Institute